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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cbb6031b0e9938c06574990444bbf5e628fd74f80c91e2c2f6707053c0d5cebe' 
  AND token = 'Mhu1YU+29dHDWBHDq68jyVRnGBq4OMXYmv3kVk9bs5A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}