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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3027e980019f508f1b682b5e20c4838f1b0e772f5a3cbabdca4a896ead12e4b8' 
  AND token = '1ZmpV21UfEQQqAWYt9zAuotdAIm/4O24L0Igu7zWfd8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}