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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8238a6487539e9260e9f0491bf8aa69d80b4f6cf2761405eb32deb3d7b0243fe' 
  AND token = 'U4tibymgZ9RIPHsPRtJzUGLWkCMMtgLo6xXE8BxVdRw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}