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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7642bfb53dad9e6dafb22494e8fb15ee26b132b8d5887066212596f47e4d62e8' 
  AND token = 'U5Py6Zxb3Z+i4fPu7Uk24Ccc7yWVvARsIWqK2qsIFk4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}