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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '852f29e2faf134ff22e3a2b5b6ca8a61bd896cacf2a300e126023c30f0a7d93c' 
  AND token = 'KGeXBIdhrQSi8uQpwxQ9cZ+VTmwxBzuaHYfqNt+TrTo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}