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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81505622152d4c19f49c4e033ed45f130cfd7d1480dbb010aea37e6b80cf3ca3' 
  AND token = 'qq3/Apd6yUXiBjVvKMGTGWsjCnBdV5DL+or8WfgNpV0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}