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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ac5972d619ef6a4abe59d3d270d22397b1dfe4f7ecdcc93c41714ac79762fd6' 
  AND token = '/o5A+AX+MwOnJuyWyv2NVe5xvOeRFTmsyk8p7lP6cuM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}