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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c1c9dc0f1c3229c429316f3410be971982e0900fe7883f1bc74cdd6a3b3e08a' 
  AND token = 'P2v2p3aZccnq1mSz1KLvGQhdvTFy/nr37p5RGNlw/qw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}