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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51360a37318cf07e6c855cc581bd2a803220b6e857a9782407f69abb8959fac2' 
  AND token = 'w+C1wmrlpBkqdYgImPxRkZpUAXu5ib6PTiwXuoHpYm0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}