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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b50089a987f06c6c6f3511f933eb081142144d2c2df1fb7831d9c73385b1d4c' 
  AND token = 'oIDpXd6PJm4t4tbQp0D/qRn016yd8TlFOvSg78cHB4Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}