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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59d5230a2eecde9c2d0565b92566b4773bf9151dea6910b8d531ef5b82610889' 
  AND token = 'JXFzce/Heg2DPELsNcWb6tVxL6SPA4d9/Zs4/HxPoAQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}