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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d73675fe1450f123a78ec4365506d07c41f16edd334994a7000de1f23cd402c' 
  AND token = 'ulBYTDUraZK5XbHj1lGlOlb6AIiA7opN6w/Mp+uRpI8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}