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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bf74c446d4b3fb9880595f80f1befc7c6c8e8f731519e7b72503ee03c32e3570' 
  AND token = 'KRlINI6+50he/PqYVv+nmYNfrOf2cDc2P06Rh3Gyf4M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}