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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '605d3d8cc384f340eb77f0440c3f5eeedeec307d8aaa9f6da3d89606cae2bf15' 
  AND token = 'WCD4DSwveBTiCiCVLAJ+hOa2aH8v0MMR2MTBpheFRhs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}