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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af12ab2ef86d571a7e6734ba9ffba38eeb1c90edfbb3bd91f47002e53577125b' 
  AND token = '7FPCxEB789pkmX+LRsGxbn+++0rBhMQkdUEixfw+Qzc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}