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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd217538329698b1cc493b035135d41c085af713320df81649e23864e8850b760' 
  AND token = 'mO0dmA8S5kAfzW6d3WEyoCvjylGeGNdnPDpAxIeNa2I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}