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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5bdba4904abfb65d718d038e8ec2b082d50910c56ced5cce56dcac45d78ffb2' 
  AND token = 'DlZGqPDvGhFnaq3UZlG4R/JYqPCMqL8hQ8/8ysMvQDc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}