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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '316ad3f2ce4255b84f1031dc65e5b8bd82e262a995ffdc52f3481c690d177e8f' 
  AND token = 'OUx8zAnUjx1/vw6LDt7nZnRPF5uZfLtZzRex06cF6Lw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}