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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d5bad9e4050891866addd7b93bac6d235f555cc931a363d280c2dc717d1f000' 
  AND token = 'jN64SvaoyVqrG3Em/MAf66npR13hTkqgenSN3GNLWwA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}