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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d0a335b65ccbdb35b764a71e4e359c2f8b9a9bdd0a8d2b393de8056e0070b52' 
  AND token = 'gN2jA2RLRv6SF4iz5t0vRuqcq2GqhgRGjjr3U6RMSiE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}