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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34cc2a5e3c4f74486690301213e0c9443c3631d772f7c83f41fe2cdb5f1fe106' 
  AND token = 'k6mJSN/3MlgQeYSERpSHKUgvX4VXFUBDmQpARopirsY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}