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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7535c0ccbe3a0c7e6765830ab45d1e04dd4239011394f223be15219ce5b3a763' 
  AND token = 'XBYdiUtmkLahl1O1k9skC6+LRxfoANWCmtfXhBDTcz8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}