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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '727542332cbbe02d8d6cde787c441a0d9167ff3fa82624a181a9617ae0b7ec59' 
  AND token = 'CM1zaCSn/Q75S+2wgU1OCjJndeiJQjx/nxIDo8DqnlE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}