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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f53c4578bf128a45579f25eac2aa861c9c81b1e0dae833d4a9dd0f2c8de4f51' 
  AND token = '/YpRyFI/Kgo6KAdT2+adspBiAxOIZ8bolPeTLqQxuGQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}