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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9dcfcbd49a6c09970460d71e979747f878583608ff180be0ca957e0036e5853e' 
  AND token = 'TYmQ/cLlgV8xCV4HUq6cNfwS+9IQYbMOV6LboDfSb48=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}