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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2ec1f1ceaf81a75279cd58770b4244ea10350a00d372f626c76fabc698bd358' 
  AND token = 'UHi8/eOk5UxvBqzGFhy3QifAFfqIFubsZe5bN78FF60=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}