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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '248231762ddb1b566a8fb7b31ce0c623653e3d3065f44e38b85fab950dfc3b9a' 
  AND token = 'uwqevhJ6HYi0fnZA9nk+sm0tvnIk/dsuSbJDCA4iLYc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}