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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '020547a27e872440a815b47a81f85ce3b48fa3bebf6bdefc7d74be2a705bbd99' 
  AND token = 'XGBS+2YZvTVm7rDp+M190hO3JMfmHON++MTE0SpTwmI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}