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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c51e6fcdd2b8ba24f998a77b8d4dda8142caddd78851f10301e039f4be53ce4' 
  AND token = 'YF63D3ew1IJgrbhCoBvbqvphctOHpp5D4Db3TeaBZTU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}