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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '13187fcc05f69916d3079cf2775c696cc9355a154532dd0e5b1011a91a1cf02e' 
  AND token = 'n6gif7F1gzdRy1jocTd7xtFBmKLW4UPZEUIIh1K987Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}