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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ede2822dd7f29a14b5319009a1c32c6cb81cea22d2428d7ecf8fe01f13fc635' 
  AND token = 'YQJYKVjfZqq2ASXXfg3nW0jCt/V3B6fV4293/XtAh7w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}