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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0dcd6b420e8d2d6b0d2eaff5bed58dc7513b2fd35c345111a9ccebe33752c978' 
  AND token = 'rHgsULDxbNI1O0fjE7OFlmbv7kJmeJRBMlBo4Cl5VYM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}