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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1c3a8054db3f38cdbec0ca66d19471b0d76f73902901ec3cc18e7f5f610d187' 
  AND token = 'hMYLTSCqA5qBfGYaWgrVxesa0fp+53fp8PjUmsf6w3U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}