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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd97d64ba83cc9a70f7e25a948080bb4722db39a12708b20c8b6de6637ba69ced' 
  AND token = 'hZjUVmQm8tkL4MZr42bDVj3rnRZ0n8uIm49l0FG0kTo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}