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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4cc33076ccd8d24e325202631acf524c33e2ee159a31b2e92e81a16c6e3be0e2' 
  AND token = 'YBeIvvcaXrwr5zGyPPrrH2uKeFm2163J/b9kJWpjS30=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}