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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4bde3dca0febc5713410d8811d21e54e13412904338e6b04b737c84c1941a29f' 
  AND token = 'C8XOlM0NJu27Hi3i5LvcM9g5TGep++9fomFPxHyg8JQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}