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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7fec1be058889f260a0d27cce998d3633fd05cc8030a3780d6baca1bbedec078' 
  AND token = 'GxVvginHx5B/A3V0cs/O0a3+HkGciWg5bdraRc1vwZQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}