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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d0f85d451501e21b0610bcbe7ed3252342d416137cd38cd5cf5059977cf0d70' 
  AND token = 'hZziW6xVOZ25dkJeZBv1saD+TeL1XPXYUIlnOAWDqF0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}