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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51554875325a4a0222c93b9bc7ead22781e55ba2ca18e1c5cb1fae5f9cc5d2f9' 
  AND token = 'DVgFYQCTq5X/WxRp+pIDGXpSoPzhnfB3Vqhu+bhxoIQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}