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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0405c68850545e7ea5878295886433c4e3b23be7c6300bb8973a7328a2cd2c0' 
  AND token = 'lCnTNpbO2up5GcnQ8GGDDqbWJYZvdJ8K3yZqfAOO/aI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}