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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f492aa43f1c75b3a6787ae9f0670721484f3fc0c91d5be06bff8a3a2b7b6830d' 
  AND token = 'dzV9CUrzYO62aY0PRUPRJfWDT3UcnjKwD3aiD1m1LSs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}