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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d76fe3449a7441b4a78a00afa831c636dd198eecbf9da76bf90a37b130f7c2c' 
  AND token = 'Empy7C/0ZRwJ8ML0SbhZ/+i4t8XyedQX2JF64O6c2uc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}