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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc6b112e90d07842340043d792a9f13d5d914612792df250c8beb800e5f6d42d' 
  AND token = 'Hzlj680MyKMIMiZ4r96Io86XRogTGqPv34Sfr2dc5Ek=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}