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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3fb9886deab17a7b9354cf2a5b81e1fd32b957cb520e753ba389df7304f88d1e' 
  AND token = 'tdDnjs03m2qv4DN0IN0hsLBG4yKIrrbDTbk5Z2hDhak=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}