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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a7cddafe9708b8df7203ac73feb535173d009dba21d272cf145e5c38fde294a' 
  AND token = 'AKcEnHy71G4dV1ejd+UzNb0EtquXmDuBPKVFZCYfCE4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}