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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b01b50a187f62bbd4488573ade0ef2f6c708ce65b7b71dd0524031bcb470b675' 
  AND token = '1SzVZJi6tf9KQFvsU+adLnmtk5S4mON+fzxOJa92YD0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}