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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '335c590c37db99948f7f3df7d168fb12ce5fc4d1aaa2e0b83ba7b94240008257' 
  AND token = 'FGx7ZrlwFWeT/WZXaR6DpCBIjkWA9B0VG7joZC0mBb4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}