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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10d63f9dc8bd23a6faa247db0eb5934f1e062043a69f15c0b57439052929e10f' 
  AND token = 'qr1QM70W0mgVgHfMyD8WminAkPCsjTK2FnbDXGAHqTQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}