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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4af83f2d628f359129d1eb0bd4b2a09831193b0da4a5902b95132f89a8c3b324' 
  AND token = 'iUZZe6ME4vuFXOUFLTP6eVcI4H1EGBDbb1YmhThgN4A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}