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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d7c08cd27df9be19f0925a6a2aec014fc22fb901a02c9627f2f98763a6ebea7' 
  AND token = 'cMaNU7msHjfaEc/LPhuFYoYxPn7KgMuD2ZJW3keiKiA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}